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5-fluorouracil - перевод на Английский
![The fives of all four suits in [[playing card]]s](https://commons.wikimedia.org/wiki/Special:FilePath/5 playing cards.jpg?width=200 "The fives of all four suits in [[playing card]]s")
![Illustration by [[Leonardo da Vinci]] of a [[regular dodecahedron]], from [[Luca Pacioli]]'s ''[[Divina proportione]]''](https://commons.wikimedia.org/wiki/Special:FilePath/De divina proportione - Illustration 13, crop.jpg?width=200 "Illustration by [[Leonardo da Vinci]] of a [[regular dodecahedron]], from [[Luca Pacioli]]'s ''[[Divina proportione]]''")
![tactility]]](https://commons.wikimedia.org/wiki/Special:FilePath/Five Senses.jpg?width=200 "tactility]]")
![International maritime signal flag for 5]]](https://commons.wikimedia.org/wiki/Special:FilePath/ICS Pennant Five.svg?width=200 "International maritime signal flag for 5]]")
![The first [[Pythagorean triple]], with a [[hypotenuse]] of <math>5</math>](https://commons.wikimedia.org/wiki/Special:FilePath/Pythagoras' Special Triples.svg?width=200 "The first [[Pythagorean triple]], with a [[hypotenuse]] of <math>5</math>")
Определение
Википедия
Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. By intravenous injection it is used for treatment of colorectal cancer, oesophageal cancer, stomach cancer, pancreatic cancer, breast cancer, and cervical cancer. As a cream it is used for actinic keratosis, basal cell carcinoma, and skin warts.
Side effects of use by injection are common. They may include inflammation of the mouth, loss of appetite, low blood cell counts, hair loss, and inflammation of the skin. When used as a cream, irritation at the site of application usually occurs. Use of either form in pregnancy may harm the baby. Fluorouracil is in the antimetabolite and pyrimidine analog families of medications. How it works is not entirely clear, but it is believed to involve blocking the action of thymidylate synthase and thus stopping the production of DNA.
Fluorouracil was patented in 1956 and came into medical use in 1962. It is on the World Health Organization's List of Essential Medicines.
